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Prevention of VEGF-induced growth and tube formation in human retinal endothelial cell by aldose reductase inhibition

OBJECTIVE: Since diabetes-induced vascular endothelial growth factor (VEGF) is implicated in retinal angiogenesis, we aimed to examine the role of aldose reductase (AR) in VEGF–induced human retinal endothelial cell (HREC) growth and tube formation. MATERIALS AND METHODS: HREC were stimulated with V...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yadav, Umesh CS, Srivastava, SK, Ramana, KV
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434238/
https://ncbi.nlm.nih.gov/pubmed/22658411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jdiacomp.2012.04.017
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