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Vascular endothelial growth factor (VEGF) induces remodeling and enhances T(H)2-mediated sensitization and inflammation in the lung

Exaggerated levels of VEGF (vascular endothelial growth factor) are present in persons with asthma, but the role(s) of VEGF in normal and asthmatic lungs has not been defined. We generated lung-targeted VEGF(165) transgenic mice and evaluated the role of VEGF in T-helper type 2 cell (T(H)2)-mediated...

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Библиографические подробности
Главные авторы: Lee, Chun Geun, Link, Holger, Baluk, Peter, Homer, Robert J, Chapoval, Svetlana, Bhandari, Vineet, Kang, Min Jong, Cohn, Lauren, Kim, Yoon Keun, McDonald, Donald M, Elias, Jack A
Формат: Artigo
Язык:Inglês
Опубликовано: 2004
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434232/
https://ncbi.nlm.nih.gov/pubmed/15378055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1105
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