Functional PstI/RsaI Polymorphism in CYP2E1 Is Associated with the Development, Progression and Poor Outcome of Gastric Cancer

BACKGROUND: Cytochrome P450 2E1 (CYP2E1), an ethanol-inducible enzyme, has been shown to metabolically activate various carcinogens, which is critical for the development and progression of cancers. It has demonstrated that CYP2E1 polymorphisms alter the transcriptional activity of the gene. However...

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Main Authors: Feng, Jin, Pan, Xiaolin, Yu, Junbo, Chen, Zheng, Xu, Hao, El-Rifai, Wael, Zhang, Guoxin, Xu, Zekuan
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434136/
https://ncbi.nlm.nih.gov/pubmed/22957075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044478
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