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Isopycnic sedimentation of DNA in metrizamide: the effect of low concentrations of ions on buoyant density and hydration

Metrizamide, an inert, non-ionic organic compound, dissolves in water to give a dense solution in which DNA bands isopycnically at a density corresponding to that of fully hydrated DNA. Density-gradient centrifugation in solutions of metrizamide has been used to determine the effects of very dilute...

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Detalhes bibliográficos
Main Authors: Birnie, G.D., MacPhail, Elizabeth, Rickwood, D.
Formato: Artigo
Idioma:Inglês
Publicado em: 1974
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC343395/
https://ncbi.nlm.nih.gov/pubmed/10793724
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