Interlaboratory Evaluation of Automated, Multiplexed Peptide Immunoaffinity Enrichment Coupled to Multiple Reaction Monitoring Mass Spectrometry for Quantifying Proteins in Plasma

The inability to quantify large numbers of proteins in tissues and biofluids with high precision, sensitivity, and throughput is a major bottleneck in biomarker studies. We previously demonstrated that coupling immunoaffinity enrichment using anti-peptide antibodies (SISCAPA) to multiple reaction mo...

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Autori principali: Kuhn, Eric, Whiteaker, Jeffrey R., Mani, D. R., Jackson, Angela M., Zhao, Lei, Pope, Matthew E., Smith, Derek, Rivera, Keith D., Anderson, N. Leigh, Skates, Steven J., Pearson, Terry W., Paulovich, Amanda G., Carr, Steven A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Technological Innovation and Resources
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433918/
https://ncbi.nlm.nih.gov/pubmed/22199228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.013854
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