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Systematic Identification of the HSP90 Regulated Proteome

HSP90 is a central player in the folding and maturation of many proteins. More than two hundred HSP90 clients have been identified by classical biochemical techniques including important signaling proteins with high relevance to human cancer pathways. HSP90 inhibition has thus become an attractive t...

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Библиографические подробности
Главные авторы: Wu, Zhixiang, Moghaddas Gholami, Amin, Kuster, Bernhard
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Biochemistry and Molecular Biology 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433914/
https://ncbi.nlm.nih.gov/pubmed/22337586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.016675
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