Pharmacoproteomic Study of Three Different Chondroitin Sulfate Compounds on Intracellular and Extracellular Human Chondrocyte Proteomes

Chondroitin sulfate (CS) is a symptomatic slow acting drug for osteoarthritis (OA) widely used for the treatment of this highly prevalent disease, characterized by articular cartilage degradation. However, little is known about its mechanism of action, and recent large scale clinical trials have rep...

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Hlavní autoři: Calamia, Valentina, Fernández-Puente, Patricia, Mateos, Jesús, Lourido, Lucía, Rocha, Beatriz, Montell, Eulália, Vergés, Josep, Ruiz-Romero, Cristina, Blanco, Francisco J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2012
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433908/
https://ncbi.nlm.nih.gov/pubmed/22203690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.013417
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