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Prostaglandin E(2) EP3 receptor regulates cyclooxygenase-2 expression in the kidney
Cyclooxygenase-2 (COX-2) is constitutively expressed and highly regulated in the thick ascending limb (TAL). As COX-2 inhibitors (Coxibs) increase COX-2 expression, we tested the hypothesis that a negative feedback mechanism involving PGE(2) EP3 receptors regulates COX-2 expression in the TAL. Sprag...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3433870/ https://ncbi.nlm.nih.gov/pubmed/22622465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00634.2011 |
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