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Regulation of glomerulotubular balance. I. Impact of dopamine on flow-dependent transport

In response to volume expansion, locally generated dopamine decreases proximal tubule reabsorption by reducing both Na/H-exchanger 3 (NHE3) and Na-K-ATPase activity. We have previously demonstrated that mouse proximal tubules in vitro respond to changes in luminal flow with proportional changes in N...

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Autori principali: Du, Zhaopeng, Yan, Qingshang, Wan, Laxiang, Weinbaum, Sheldon, Weinstein, Alan M., Wang, Tong
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433864/
https://ncbi.nlm.nih.gov/pubmed/22552936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00531.2011
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