Staphylococcus aureus Staphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis

The CXC chemokine receptor 2 (CXCR2) on neutrophils, which recognizes chemokines produced at the site of infection, plays an important role in antimicrobial host defenses such as neutrophil activation and chemotaxis. Staphylococcus aureus is a successful human pathogen secreting a number of proteoly...

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Autori principali: Laarman, Alexander J, Mijnheer, Gerdien, Mootz, Joe M, van Rooijen, Willemien J M, Ruyken, Maartje, Malone, Cheryl L, Heezius, Erik C, Ward, Richard, Milligan, Graeme, van Strijp, Jos A G, de Haas, Carla J C, Horswill, Alexander R, van Kessel, Kok P M, Rooijakkers, Suzan H M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433787/
https://ncbi.nlm.nih.gov/pubmed/22850671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.212
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