Generation of DNA single-strand displacement by compromised nucleotide excision repair

Nucleotide excision repair (NER) is a precisely coordinated process essential to avoid DNA damage-induced cellular malfunction and mutagenesis. Here, we investigate the mechanistic details and effects of the NER machinery when it is compromised by a pathologically significant mutation in a subunit o...

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Autores principales: Godon, Camille, Mourgues, Sophie, Nonnekens, Julie, Mourcet, Amandine, Coin, Fréderic, Vermeulen, Wim, Mari, Pierre-Olivier, Giglia-Mari, Giuseppina
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433779/
https://ncbi.nlm.nih.gov/pubmed/22863773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.193
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