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Xanthine Functionalized Congeners as Potent Ligands at A(2)-Adenosine Receptors(,)

Amide derivatives of a carboxylic acid congener of 1,3-dialkylxanthine, having a 4-[(carboxymethyl)oxy]phenyl substituent at the 8-position, have been synthesized in order to identify potent antagonists at A(2)-adenosine receptors stimulatory to adenylate cyclase in platelets. Distal structural feat...

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Detalles Bibliográficos
Main Authors: Jacobson, Kenneth A., Ukena, Dieter, Padgett, William, Daly, John W., Kirk, Kenneth L.
Formato: Artigo
Idioma:Inglês
Publicado: 1987
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433718/
https://ncbi.nlm.nih.gov/pubmed/3806597
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