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A culture system to study oligodendrocyte myelination-processes using engineered nanofibers

Current methods for studying central nervous system myelination necessitate permissive axonal substrates conducive for myelin wrapping by oligodendrocytes. We have developed a neuron-free culture system in which electron-spun nanofibers of varying sizes substitute for axons as a substrate for oligod...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lee, Seonok, Leach, Michelle K., Redmond, Stephanie A., Chong, S.Y. Christin, Mellon, Synthia H., Tuck, Samuel J., Feng, Zhang-Qi, Corey, Joseph M., Chan, Jonah R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433633/
https://ncbi.nlm.nih.gov/pubmed/22796663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2105
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