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The Diverse Ligand Repertoire of the Receptor for Advanced Glycation Endproducts & Pathways to the Complications of Diabetes
The multi-ligand receptor RAGE was discovered on account of its ability to bind and transduce the cell stress-provoking signals of advanced glycation endproducts (AGEs). The finding that RAGE also bound pro-inflammatory molecules set the stage for linking RAGE and inflammation to the pathogenesis of...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3433629/ https://ncbi.nlm.nih.gov/pubmed/22750165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vph.2012.06.004 |
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