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Distinct age-dependent effects of methylphenidate on developing and adult prefrontal neurons

BACKGROUND: Methylphenidate (MPH) has long been used to treat attention deficit-hyperactivity disorder (ADHD); however, its cellular mechanisms of action and potential effects on prefrontal cortical circuitry are not well understood, particularly in the developing brain system. A clinically-relevant...

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Autors principals: Urban, Kimberly R., Waterhouse, Barry D., Gao, Wen-Jun
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433628/
https://ncbi.nlm.nih.gov/pubmed/22609367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2012.04.018
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