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Dynamics of Forced Nucleosome Unraveling and Role of Nonuniform Histone-DNA Interactions
A coarse-grained model of the nucleosome is introduced to investigate the dynamics of force-induced unwrapping of DNA from histone octamers. In this model, the DNA is treated as a charged, discrete worm-like chain, and the octamer is treated as a rigid cylinder carrying a positively charged superhel...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3433614/ https://ncbi.nlm.nih.gov/pubmed/23009848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.07.043 |
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