Inclusion of Many-Body Effects in the Additive CHARMM Protein CMAP Potential Results in Enhanced Cooperativity of α-Helix and β-Hairpin Formation

Folding simulations on peptides and proteins using empirical force fields have demonstrated the sensitivity of the results to details of the backbone potential. A recently revised version of the additive CHARMM protein force field, which includes optimization of the backbone CMAP potential to achiev...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Best, Robert B., Mittal, Jeetain, Feig, Michael, MacKerell, Alexander D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2012
Pynciau:
Proteins and Nucleic Acids
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433603/
https://ncbi.nlm.nih.gov/pubmed/23009854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.07.042
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg