Reduced Risk of Plasmodium vivax Malaria in Papua New Guinean Children with Southeast Asian Ovalocytosis in Two Cohorts and a Case-Control Study

BACKGROUND: The erythrocyte polymorphism, Southeast Asian ovalocytosis (SAO) (which results from a 27-base pair deletion in the erythrocyte band 3 gene, SLC4A1Δ27) protects against cerebral malaria caused by Plasmodium falciparum; however, it is unknown whether this polymorphism also protects agains...

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Main Authors: Rosanas-Urgell, Anna, Lin, Enmoore, Manning, Laurens, Rarau, Patricia, Laman, Moses, Senn, Nicolas, Grimberg, Brian T., Tavul, Livingstone, Stanisic, Danielle I., Robinson, Leanne J., Aponte, John J., Dabod, Elijah, Reeder, John C., Siba, Peter, Zimmerman, Peter A., Davis, Timothy M. E., King, Christopher L., Michon, Pascal, Mueller, Ivo
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433408/
https://ncbi.nlm.nih.gov/pubmed/22973182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1001305
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