Reduced Risk of Plasmodium vivax Malaria in Papua New Guinean Children with Southeast Asian Ovalocytosis in Two Cohorts and a Case-Control Study

BACKGROUND: The erythrocyte polymorphism, Southeast Asian ovalocytosis (SAO) (which results from a 27-base pair deletion in the erythrocyte band 3 gene, SLC4A1Δ27) protects against cerebral malaria caused by Plasmodium falciparum; however, it is unknown whether this polymorphism also protects agains...

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Main Authors: Rosanas-Urgell, Anna, Lin, Enmoore, Manning, Laurens, Rarau, Patricia, Laman, Moses, Senn, Nicolas, Grimberg, Brian T., Tavul, Livingstone, Stanisic, Danielle I., Robinson, Leanne J., Aponte, John J., Dabod, Elijah, Reeder, John C., Siba, Peter, Zimmerman, Peter A., Davis, Timothy M. E., King, Christopher L., Michon, Pascal, Mueller, Ivo
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433408/
https://ncbi.nlm.nih.gov/pubmed/22973182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1001305
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