Reduced Risk of Plasmodium vivax Malaria in Papua New Guinean Children with Southeast Asian Ovalocytosis in Two Cohorts and a Case-Control Study

BACKGROUND: The erythrocyte polymorphism, Southeast Asian ovalocytosis (SAO) (which results from a 27-base pair deletion in the erythrocyte band 3 gene, SLC4A1Δ27) protects against cerebral malaria caused by Plasmodium falciparum; however, it is unknown whether this polymorphism also protects agains...

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Hlavní autoři: Rosanas-Urgell, Anna, Lin, Enmoore, Manning, Laurens, Rarau, Patricia, Laman, Moses, Senn, Nicolas, Grimberg, Brian T., Tavul, Livingstone, Stanisic, Danielle I., Robinson, Leanne J., Aponte, John J., Dabod, Elijah, Reeder, John C., Siba, Peter, Zimmerman, Peter A., Davis, Timothy M. E., King, Christopher L., Michon, Pascal, Mueller, Ivo
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433408/
https://ncbi.nlm.nih.gov/pubmed/22973182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1001305
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