KETAMINE-INDUCED NEUROAPOPTOSIS IN THE FETAL AND NEONATAL RHESUS MACAQUE BRAIN

BACKGROUND: Exposure of rhesus macaque fetuses for 24 h, or neonates for 9 h, to ketamine anesthesia causes neuroapoptosis in the developing brain. The present study further clarifies the minimum exposure required for, and the extent and spatial distribution of, ketamine-induced neuroapoptosis in rh...

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Main Authors: Brambrink, Ansgar M., Evers, Alex S., Avidan, Michael S., Farber, Nuri B., Smith, Derek J., Martin, Lauren D., Dissen, Gregory A., Creeley, Catherine E., Olney, John W.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433282/
https://ncbi.nlm.nih.gov/pubmed/22222480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e318242b2cd
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