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Passing the baton: The HIF switch
Hypoxia is an inadequate oxygen supply to tissues and cells, which can restrict their function. The hypoxic response is primarily mediated by the hypoxia-inducible transcription factors, HIF-1 and HIF-2, which have both overlapping and unique target genes. HIF target gene activation is highly contex...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3433036/ https://ncbi.nlm.nih.gov/pubmed/22818162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2012.06.004 |
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