Relationship between Changes in Plasma Adiponectin Concentration and Insulin Sensitivity after Niacin Therapy

BACKGROUND: Niaspan® (extended-release niacin) is a nicotinic acid formulation used to treat dyslipidemia in obese subjects. Niaspan binds to the GPR109A receptor in adipose tissue and stimulates adiponectin secretion, which should improve insulin sensitivity. However, Niaspan therapy often causes i...

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Detalhes bibliográficos
Main Authors: Fraterrigo, Gemma, Fabbrini, Elisa, Mittendorfer, Bettina, O'Rahilly, Stephen, Scherer, Philipp E., Patterson, Bruce W., Klein, Samuel
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2012
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433009/
https://ncbi.nlm.nih.gov/pubmed/22969777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000340037
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