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A novel Drosophila SOD2 mutant demonstrates a role for mitochondrial ROS in neurodevelopment and disease

Reactive oxygen species (ROS) play essential roles in cell signaling, survival, and homeostasis. Aberrant ROS lead to disease and contribute to the aging process. Numerous enzymes and vigilant antioxidant pathways are required to regulate ROS for normal cellular health. Mitochondria are a major sour...

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Detalhes bibliográficos
Main Authors: Celotto, Alicia M, Liu, Zhaohui, VanDemark, Andrew P, Palladino, Michael J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Inc 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432965/
https://ncbi.nlm.nih.gov/pubmed/22950046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.73
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