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LAAT-1 is the Lysosomal Lysine/Arginine Transporter that Maintains Amino Acid Homeostasis
Defective catabolite export from lysosomes results in lysosomal storage diseases in humans. Mutations in the cystine transporter gene CTNS cause cystinosis, but other lysosomal amino acid transporters are poorly characterized at the molecular level. Here we identified the C. elegans lysosomal lysine...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3432903/ https://ncbi.nlm.nih.gov/pubmed/22822152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1220281 |
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