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A Crosstalk Imbalance Between p27(Kip1) and Its Interacting Molecules Enhances Breast Carcinogenesis
p27(Kip1) (p27) is an inhibitor of cyclin/cyclin-dependent kinase complexes, the nuclear loss of which indicates poor prognoses in various solid tumors. In breast cancer cells, the p27 expression level usually decreases during tumor development and progression. In addition, p27 cytoplasmic mislocali...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Mary Ann Liebert, Inc.
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3432864/ https://ncbi.nlm.nih.gov/pubmed/22690887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cbr.2010.0802 |
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