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A Crosstalk Imbalance Between p27(Kip1) and Its Interacting Molecules Enhances Breast Carcinogenesis

p27(Kip1) (p27) is an inhibitor of cyclin/cyclin-dependent kinase complexes, the nuclear loss of which indicates poor prognoses in various solid tumors. In breast cancer cells, the p27 expression level usually decreases during tumor development and progression. In addition, p27 cytoplasmic mislocali...

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Autores principales: He, Weiwei, Wang, Xueting, Chen, Longbang, Guan, Xiaoxiang
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432864/
https://ncbi.nlm.nih.gov/pubmed/22690887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cbr.2010.0802
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