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A Crosstalk Imbalance Between p27(Kip1) and Its Interacting Molecules Enhances Breast Carcinogenesis

p27(Kip1) (p27) is an inhibitor of cyclin/cyclin-dependent kinase complexes, the nuclear loss of which indicates poor prognoses in various solid tumors. In breast cancer cells, the p27 expression level usually decreases during tumor development and progression. In addition, p27 cytoplasmic mislocali...

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Bibliographic Details
Main Authors: He, Weiwei, Wang, Xueting, Chen, Longbang, Guan, Xiaoxiang
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432864/
https://ncbi.nlm.nih.gov/pubmed/22690887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cbr.2010.0802
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