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Long-range genomic interactions epigenetically regulate the expression of a cytokine receptor

Current research on the cytokine-mediated signalling towards the polarization and differentiation of a T-helper cell lineage lacks mechanistic insights on the transcriptional regulation of cytokine receptor genes. Here, we propose a new mechanism for the transcriptional regulation of the interferon...

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Détails bibliographiques
Auteurs principaux: Deligianni, Chrysoula, Spilianakis, Charalampos G
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432804/
https://ncbi.nlm.nih.gov/pubmed/22836578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.112
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