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Proteomic identification of a direct role for cyclin D1 in DNA damage repair
The human CCND1 gene, encoding a cell cycle protein cyclin D1, is one of the most frequently amplified genes in human cancers. Cyclin D1 activates cyclin dependent kinases CDK4 and CDK6 and drives cell proliferation. Beyond the cell cycle role, the full repertoire of cyclin D1 functions in cancer ce...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3432743/ https://ncbi.nlm.nih.gov/pubmed/22915759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3549 |
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