Anti-EMP2 diabody blocks Epithelial Membrane Protein 2 (EMP2) and FAK mediated collagen gel contraction in ARPE-19 cells

Epithelial membrane protein 2 (EMP2) regulates collagen gel contraction by the retinal pigment epithelium cell line ARPE-19 by modulating FAK activation. Collagen gel contraction is one in vitro model for an aberrant wound healing response, proliferative vitreoretinopathy (PVR), which occurs as a co...

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Bibliographic Details
Main Authors: Morales, Shawn A., Telander, David G., Mareninov, Sergey, Nagy, Agnes, Wadehra, Madhuri, Braun, Jonathan, Gordon, Lynn K.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432690/
https://ncbi.nlm.nih.gov/pubmed/22728127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2012.06.002
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