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Cetuximab Therapy in Head and Neck Cancer: Immune Modulation with Interleukin-12 and Other Natural Killer Cell Activating Cytokines
We hypothesized that IL-12 would enhance the anti-tumor activity of the anti-HER1 antibody cetuximab against squamous cell carcinomas of the head and neck (SCCHN) by activating the FcR effector mechanisms of NK cells. All cell lines showed high expression of HER1 by flow cytometry and immunoblot ana...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3432674/ https://ncbi.nlm.nih.gov/pubmed/22770960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2012.05.035 |
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