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Behavioral analysis of NR2C knockout mouse reveals deficit in working memory and acquisition of conditioned fear

N -methyl-D-aspartate (NMDA) receptors play an important role in excitatory neurotransmission and mediate synaptic plasticity associated with learning and memory. NMDA receptors are composed of two NR1 and two NR2 subunits and the identity of the NR2 subunit confers unique electrophysiologic and pha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hillman, Brandon G., Gupta, Subhash C., Stairs, Dustin J., Buonanno, Andres, Dravid, Shashank M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432405/
https://ncbi.nlm.nih.gov/pubmed/21295149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nlm.2011.01.008
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