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Use of Yeast as a System to Study Amyloid Toxicity

The formation of amyloid-like fibrils is a hallmark of several neurodegenerative diseases. How the assembly of amyloid-like fibrils contributes to cell death is a major unresolved question in the field. The budding yeast Saccharomyces cerevisiae is a powerful model organism to study basic mechanisms...

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Detalhes bibliográficos
Main Authors: Summers, Daniel W., Cyr, Douglas M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432305/
https://ncbi.nlm.nih.gov/pubmed/21115125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2010.11.007
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