Effective Non-Viral Delivery of siRNA to Acute Myeloid Leukemia Cells with Lipid-Substituted Polyethylenimines

Use of small interfering RNA (siRNA) is a promising approach for AML treatment as the siRNA molecule can be designed to specifically target proteins that contribute to aberrant cell proliferation in this disease. However, a clinical-relevant means of delivering siRNA molecules must be developed, as...

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Bibliografiske detaljer
Main Authors: Landry, Breanne, Aliabadi, Hamidreza Montazeri, Samuel, Anuja, Gül-Uludağ, Hilal, Jiang, Xiaoyan, Kutsch, Olaf, Uludağ, Hasan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432090/
https://ncbi.nlm.nih.gov/pubmed/22952927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044197
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