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New Ataxic Tottering-6j Mouse Allele Containing a Cacna1a Gene Mutation

Voltage-gated Ca(2+) (Ca(v)) channels control neuronal functions including neurotransmitter release and gene expression. The Cacna1a gene encodes the α1 subunit of the pore-forming Ca(v)2.1 channel. Mice with mutations in this gene form useful tools for defining channel functions. The recessive atax...

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Detalhes bibliográficos
Main Authors: Li, Weidong, Zhou, Ying, Tian, Xiaoli, Kim, Tae Yeon, Ito, Namiko, Watanabe, Kaori, Tsuji, Akiko, Niimi, Kimie, Aoyama, Yo, Arai, Takashi, Takahashi, Eiki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432086/
https://ncbi.nlm.nih.gov/pubmed/22952933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044230
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