The prognostic value of expression of HIF1α, EGFR and VEGF-A, in localized prostate cancer for intermediate- and high-risk patients treated with radiation therapy with or without androgen deprivation therapy

PURPOSE: Androgens stimulate the production of hypoxia-inducible factor (HIF1α) and ultimately vascular endothelial growth factor (VEGF-A). Additionally, epithelial growth factor (EGF) mediates HIF1α production. Carbonic anhydrase IX (CAIX) expression is associated with tumor cell hypoxia in a varie...

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Main Authors: Weber, Damien C, Tille, Jean-Christophe, Combescure, Christophe, Egger, Jean-François, Laouiti, Mahomet, Hammad, Karim, Granger, Perrine, Rubbia-Brandt, Laura, Miralbell, Raymond
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432017/
https://ncbi.nlm.nih.gov/pubmed/22546016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-7-66
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