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Interactions of norharman and harman with DNA.

The interactions of norharman (9H-pyrido [3,4-b] indole) and harman (1-methyl-9H-pyrido [3,4-b] indole) with DNA were studied. DNA caused remarkable fluorescence quenching and change in the absorption spectra of the dyes. Scatchard plots obtained by optical titration gave Kd values of 2.2 X 10(-5)M...

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Detalhes bibliográficos
Main Authors: Hayashi, K, Nagao, M, Sugimura, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1977
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC343192/
https://ncbi.nlm.nih.gov/pubmed/593881
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