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2,3-Dihydro-1H-cyclopenta[b]quinoline Derivatives as Acetylcholinesterase Inhibitors—Synthesis, Radiolabeling and Biodistribution

In the present study we describe the synthesis and biological assessment of new tacrine analogs in the course of inhibition of acetylcholinesterase. The obtained molecules were synthesized in a condensation reaction between activated 6-BOC-hydrazinopyridine-3-carboxylic acid and 8-aminoalkyl derivat...

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Bibliografiske detaljer
Main Authors: Szymański, Paweł, Lázničková, Alice, Lázniček, Milan, Bajda, Marek, Malawska, Barbara, Markowicz, Magdalena, Mikiciuk-Olasik, Elżbieta
Format: Artigo
Sprog:Inglês
Udgivet: Molecular Diversity Preservation International (MDPI) 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431846/
https://ncbi.nlm.nih.gov/pubmed/22949848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms130810067
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