Endosomal Sorting Complex Required for Transport (ESCRT) Complexes Induce Phase-separated Microdomains in Supported Lipid Bilayers

The endosomal sorting complex required for transport (ESCRT) system traffics ubiquitinated cargo to lysosomes via an unusual membrane budding reaction that is directed away from the cytosol. Here, we show that human ESCRT-II self-assembles into clusters of 10–100 molecules on supported lipid bilayer...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Boura, Evzen, Ivanov, Vassili, Carlson, Lars-Anders, Mizuuchi, Kiyoshi, Hurley, James H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Membrane Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431677/
https://ncbi.nlm.nih.gov/pubmed/22718754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.378646
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