Endosomal Sorting Complex Required for Transport (ESCRT) Complexes Induce Phase-separated Microdomains in Supported Lipid Bilayers

The endosomal sorting complex required for transport (ESCRT) system traffics ubiquitinated cargo to lysosomes via an unusual membrane budding reaction that is directed away from the cytosol. Here, we show that human ESCRT-II self-assembles into clusters of 10–100 molecules on supported lipid bilayer...

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Hauptverfasser: Boura, Evzen, Ivanov, Vassili, Carlson, Lars-Anders, Mizuuchi, Kiyoshi, Hurley, James H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Membrane Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431677/
https://ncbi.nlm.nih.gov/pubmed/22718754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.378646
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