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Cigarette Smoke Induces MUC5AC Protein Expression through the Activation of Sp1

Cigarette smoke (CS) exposure is associated with increased mucus production and chronic obstructive pulmonary disease (COPD). MUC5AC is the major inducible mucus gene in the airway. The purpose of this investigation was to elucidate the mechanisms of CS-induced activation of MUC5AC gene transcriptio...

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Detalhes bibliográficos
Main Authors: Di, Y. Peter, Zhao, Jinming, Harper, Richart
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431669/
https://ncbi.nlm.nih.gov/pubmed/22700966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.334375
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