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The Periplasmic Loop Provides Stability to the Open State of the CorA Magnesium Channel

Crystal structures of the CorA Mg(2+) channel have suggested that metal binding in the cytoplasmic domain stabilizes the pentamer in a closed conformation. The open “metal free” state of the channel is, however, still structurally uncharacterized. Here, we have attempted to map conformational states...

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Autors principals: Palombo, Isolde, Daley, Daniel O., Rapp, Mikaela
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431667/
https://ncbi.nlm.nih.gov/pubmed/22722933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.371484
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