Tetrameric Structure of the GlfT2 Galactofuranosyltransferase Reveals a Scaffold for the Assembly of Mycobacterial Arabinogalactan

Biosynthesis of the mycobacterial cell wall relies on the activities of many enzymes, including several glycosyltransferases (GTs). The polymerizing galactofuranosyltransferase GlfT2 (Rv3808c) synthesizes the bulk of the galactan portion of the mycolyl-arabinogalactan complex, which is the largest c...

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Bibliographic Details
Main Authors: Wheatley, Robert W., Zheng, Ruixiang Blake, Richards, Michele R., Lowary, Todd L., Ng, Kenneth K. S.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431634/
https://ncbi.nlm.nih.gov/pubmed/22707726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.347484
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