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Nonmuscle Myosin II Is Required for Internalization of the Epidermal Growth Factor Receptor and Modulation of Downstream Signaling

Ligand-induced internalization of the epidermal growth factor receptor (EGFR) is an important process for regulating signal transduction, cellular dynamics, and cell-cell communication. Here, we demonstrate that nonmuscle myosin II (NM II) is required for the internalization of the EGFR and to trigg...

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Detalhes bibliográficos
Principais autores: Kim, Jong Hyun, Wang, Aibing, Conti, Mary Anne, Adelstein, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431632/
https://ncbi.nlm.nih.gov/pubmed/22718763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.304824
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