Imatinib after induction for treatment of children and adolescents with Philadelphia-chromosome-positive acute lymphoblastic leukaemia (EsPhALL): a randomised, open-label, intergroup study

BACKGROUND: Trials of imatinib have provided evidence of activity in adults with Philadelphia-chromosome-positive acute lymphoblastic leukaemia (ALL), but the drug's role when given with multidrug chemotherapy to children is unknown. This study assesses the safety and efficacy of oral imatinib...

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Detalhes bibliográficos
Main Authors: Biondi, Andrea, Schrappe, Martin, De Lorenzo, Paola, Castor, Anders, Lucchini, Giovanna, Gandemer, Virginie, Pieters, Rob, Stary, Jan, Escherich, Gabriele, Campbell, Myriam, Li, Chi-Kong, Vora, Ajay, Aricò, Maurizio, Röttgers, Silja, Saha, Vaskar, Valsecchi, Maria Grazia
Formato: Artigo
Idioma:Inglês
Publicado em: Lancet Pub. Group 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431502/
https://ncbi.nlm.nih.gov/pubmed/22898679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(12)70377-7
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