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Linking disease associations with regulatory information in the human genome

Genome-wide association studies have been successful in identifying single nucleotide polymorphisms (SNPs) associated with a large number of phenotypes. However, an associated SNP is likely part of a larger region of linkage disequilibrium. This makes it difficult to precisely identify the SNPs that...

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Detalhes bibliográficos
Main Authors: Schaub, Marc A., Boyle, Alan P., Kundaje, Anshul, Batzoglou, Serafim, Snyder, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431491/
https://ncbi.nlm.nih.gov/pubmed/22955986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.136127.111
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