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Toxicokinetic-toxicodynamic modelling of survival of Gammarus pulex in multiple pulse exposures to propiconazole: model assumptions, calibration data requirements and predictive power

Toxicokinetic-toxicodynamic (TKTD) models quantify the time-course of internal concentration, which is defined by uptake, elimination and biotransformation (TK), and the processes which lead to the toxic effects (TD). TKTD models show potential in predicting pesticide effects in fluctuating concentr...

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書誌詳細
主要な著者: Nyman, Anna-Maija, Schirmer, Kristin, Ashauer, Roman
フォーマット: Artigo
言語:Inglês
出版事項: Springer US 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431474/
https://ncbi.nlm.nih.gov/pubmed/22562719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10646-012-0917-0
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