Disrupted Organization of RFamide Pathways in the Hypothalamus Is Associated with Advanced Puberty in Female Rats Neonatally Exposed to Bisphenol A

Hypothalamic neurons, which produce the kisspeptin family of peptide hormones (Kp), are critical for initiating puberty and maintaining estrous cyclicity by stimulating gonadotropin-releasing hormone (GnRH) release. Conversely, RFamide-related peptide-3 (RFRP3) neurons inhibit GnRH activity. It has...

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Detalhes bibliográficos
Main Authors: Losa-Ward, Sandra M., Todd, Karina L., McCaffrey, Katherine A., Tsutsui, Kazuyoshi, Patisaul, Heather B.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431424/
https://ncbi.nlm.nih.gov/pubmed/22572997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.112.100826
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