The Minimal Deneddylase Core of the COP9 Signalosome Excludes the Csn6 MPN(−) Domain

The COP9 signalosome (CSN) is a eukaryotic protein complex, which regulates a wide range of biological processes mainly through modulating the cullin ubiquitin E3 ligases in the ubiquitin-proteasome pathway. The CSN possesses a highly conserved deneddylase activity that centers at the JAMM motif of...

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Main Authors: Pick, Elah, Golan, Amnon, Zimbler, Jacob Z., Guo, Liquan, Sharaby, Yehonatan, Tsuge, Tomohiko, Hofmann, Kay, Wei, Ning
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431379/
https://ncbi.nlm.nih.gov/pubmed/22956996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043980
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