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Interplay of Gene Expression Noise and Ultrasensitive Dynamics Affects Bacterial Operon Organization

Bacterial chromosomes are organized into polycistronic cotranscribed operons, but the evolutionary pressures maintaining them are unclear. We hypothesized that operons alter gene expression noise characteristics, resulting in selection for or against maintaining operons depending on network architec...

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Detalhes bibliográficos
Main Authors: Ray, J. Christian J, Igoshin, Oleg A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431296/
https://ncbi.nlm.nih.gov/pubmed/22956903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002672
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